Strategy Selection Resources

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To successfully address Substance misuse and related behavioral health problems it is necessary to have information about the effectiveness of available programs and practices. Determining which options have the greatest potential to work well in unique settings and how to proceed if no viable options are available is also important. This resource from the Substance Abuse and Mental Health Services Administration (SAMHSA) has developed this guidance document, Selecting Best-Fit Programs and Practices: Guidance for Substance Misuse Prevention Practitioners, to meet these needs.

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The purpose of this guidance is to assist State and community planners in applying the Substance Abuse and Mental Health Services Administration’s (SAMHSA’s) Strategic Prevention Framework (SPF) to identify and select evidence-based interventions that address local needs and reduce substance abuse problems. This document describes the Strategic Prevention Framework and promotes implementing evidence-based practices for prevention in communities across the country.


This document is to assist community leaders,local and regional organizers, non-profit groups, law enforcement, public health, and members of the public in understanding and navigating effective strategies to prevent opioid overdose in their community. The CDC also held a webinar on using the document and reviewing it’s contents. The webinar recording can be found here.

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EMS care has evolve from a system largely based on tradition and best practice to one with a growing evidence base supporting procedures and protocols.